Site Directed Mutagenesis - For Any Downstream Application

Site-directed mutagenesis
kit solutions for you

Site-directed mutagenesis kit: Precise DNA modifications

(SDM) can help reveal the secrets of gene regulation

Using the site directed mutagenesis approach the complete behaviour or functionality of a gene can be altered. Depending on the number of mutations/changes it is often very useful to use the synthetic gene synthesis service. This process is really fast and offers highest flexibility in gene alterations.

If different "variants" of one gene are needed a combination of gene synthesis and SDM might be more efficient. Just send us your request.

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Below you can find a wide range of possible SDM approaches

Point mutations - a small number of base exchanges
at one target site within a gene
Insertions - from a few bases up to long strechtes of additional bases
Deletions - remove unwanted parts of your gene
sequence
Large Substitutions - a longer stretch with several mutations at one target site
Multi-position exchanges - alterations of the gene throughout many positions or the complete
gene sequence

For all our SDM Services we offer

Guaranteed confidentiality
All confidentiality-sensitive steps are handled at our DNA campus: DNA Oligonucleotide synthesis, Sanger Sequencing and the SDM itself. Your data won't leave our Campus
100% accuracy of your mutated region
All mutated sequences will be verified with double-stranded DNA Sequencing and a restriction digest for 100% accuracy
Long term expertise in SDM
The team in our lab has been working with SDM for many years and the routine performance of SDMs adds additional know how every day.
Specific amplification method
Our SDM is based on specific amplification methods to minimise errors and improve the quality